Pantothenic Acid Its Derivatives

The daily excretion of riboflavin biotin, pantothenic acid, and nicotinic acid derivatives by normals.

Microbic Decomposition of Pantothenic Acid.

The metabolism of pantothenic acid.

The formulation of this pathway was based on: (a) the finding that cysteine supplies the sulfur-containing moiety of CoA (3,4); (b) the activities of pantetheine and pantothenylcysteine as growth factors for Acetobacter suboxydans (4-6) and Lactobacillus helveticus (7); (c) the presence of enzymes in these two organisms and also in Lactobacillus bulgur&s which decarboxylate pantothenylcysteine ...

A Stereospecific Synthesis of Pantothenic Acid Derivatives in Prebiotic Molecular Evolution on Earth

A set of chemical reactions is proposed to account for the formation of pantothenic acid derivatives from a primeval atmosphere composed of ammonia, formaldehyde, propyne, ethyne, hydrogen sulfide, hydrogen and water. Three precursor molecules are initially formed; a di-adduct of propyne and the catalyst Mg.porphin, azetidine2one, and 2-amino ethyl mercaptan. These then react sequentially to fo...

Hypolipidemic effect of pantothenic acid derivatives in mice with hypothalamic obesity induced by aurothioglucose.

The hypolipidemic effects of pantothenic acid derivatives (phosphopantothenate, panthenol and pantethine) were studied in mice with hypothalamic obesity. Hypothalamic obesity in mice was induced by single injection of aurothioglucose (300 mg/kg body wt, i.p.). All the tested substances were administered during the last 10 days before decapitation (i.m., of dosage equivalent to 150 mg/kg body wt...